作者
Shervin Tabrizi, Lorenzo Trippa, Daniel Cagney, Ayal A Aizer, Shyam Tanguturi, Steffen Ventz, Geoffrey Fell, Jennifer R Bellon, Harvey Mamon, Paul L Nguyen, Anthony V D’Amico, Daphne Haas-Kogan, Brian M Alexander, Rifaquat Rahman
发表日期
2021/3/1
期刊
JAMA Network Open
卷号
4
期号
3
页码范围
e213304-e213304
出版商
American Medical Association
简介
Importance
During the COVID-19 pandemic, cancer therapy may put patients at risk of SARS-CoV-2 infection and mortality. The impacts of proposed alternatives on reducing infection risk are unknown.
Objective
To investigate how the COVID-19 pandemic is associated with the risks and benefits of standard radiation therapy (RT).
Design, Setting, and Participants
This comparative effectiveness study used estimated individual patient–level data extracted from published Kaplan-Meier survival figures from 8 randomized clinical trials across oncology from 1993 to 2014 that evaluated the inclusion of RT or compared different RT fractionation regimens. Included trials were Dutch TME and TROG 01.04 examining rectal cancer; CALGB 9343, OCOG hypofractionation trial, FAST-Forward, and NSABP B-39 examining early stage breast cancer, and CHHiP and HYPO-RT-PC examining prostate cancer. Risk of SARS-CoV-2 …
学术搜索中的文章
S Tabrizi, L Trippa, D Cagney, AA Aizer, S Tanguturi… - JAMA Network Open, 2021