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Safety and tracking stability are crucial for safety-critical systems such as self-driving cars, autonomous mobile robots, and industrial manipulators. To efficiently control safety-critical systems to ensure their safety and achieve tracking stability, accurate system dynamic models are usually required. However, accurate system models are not always available in practice. In this paper, a learning-based safety-stability-driven control (LBSC) algorithm is presented to guarantee the safety and tracking stability for nonlinear safety-critical systems subject to control input constraints under model uncertainties. Gaussian Processes (GPs) are employed to learn the model error between the nominal model and the actual system dynamics, and the estimated mean and variance of the model error are used to quantify a high-confidence uncertainty bound. Using this estimated uncertainty bound, a safety barrier constraint is devised …