作者
Ahmad R Sedaghat, Zhe Zhang, Shahnaz Begum, Robert Palermo, Simon Best, Karen M Ulmer, Marshall Levine, Eva Zinreich, Barbara P Messing, Dorothy Gold, Annie A Wu, Kevin J Niparko, Jeanne Kowalski, Richard M Hirata, John R Saunders, William H Westra, Sara I Pai
发表日期
2009/8
期刊
The Laryngoscope
卷号
119
期号
8
页码范围
1542-1549
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
Objectives/Hypothesis
The human papillomavirus (HPV) has been identified as a causative factor in 20% to 25% of all head and neck squamous cell carcinomas (HNSCC). Ongoing research suggests that the presence of HPV DNA in HNSCC predicts a positive prognosis with respect to disease‐free and overall survival. However, most studies have been limited by the heterogeneity in treatment regimens and/or anatomic subsites of tumor origin. In this study, we correlate clinical outcomes with HPV status for patients with oropharyngeal carcinomas who were uniformly treated with a concurrent chemoradiation treatment protocol.
Study Design
Retrospective study.
Methods
Demographic and clinicopathologic parameters, including age at diagnosis, gender, race, smoking and alcohol history, tumor stage and grade, locoregional recurrence, metastatic spread, recurrence‐free survival, overall survival and disease …
引用总数
学术搜索中的文章
AR Sedaghat, Z Zhang, S Begum, R Palermo, S Best… - The Laryngoscope, 2009