作者
Chong Huang, Siavash Mazdeyasna, Li Chen, Elie G Abu Jawdeh, Henrietta S Bada, Kathryn E Saatman, Lei Chen, Guoqiang Yu
发表日期
2019/9/1
期刊
Neuroimage
卷号
198
页码范围
160-169
出版商
Academic Press
简介
Continuous and longitudinal imaging of cerebral blood flow (CBF) variations provide vital information to investigate pathophysiology and interventions for a variety of neurological and cerebral diseases. An innovative noncontact speckle contrast diffuse correlation tomography (scDCT) system was downscaled and adapted for noninvasive imaging of CBF distributions in rat brain through intact scalp and skull. Algorithms for 2D mapping and 3D image reconstruction of CBF distributions were developed and optimized. The continuous imaging capability of the system was shown by imaging global CBF increases during CO2 inhalations and regional CBF decreases across two hemispheres during sequential unilateral and bilateral common carotid artery ligations. The longitudinal imaging capability was demonstrated by imaging CBF variations over a long recovery period of 14 days after an acute stroke. Compared to …
学术搜索中的文章
C Huang, S Mazdeyasna, L Chen, EGA Jawdeh… - Neuroimage, 2019