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A cyclist crash with an open vehicle door can result in serious injury, sometimes fatal, outcomes. However, little is known about the frequency and range of injury outcomes of this crash type or the contributing factors. In this study, the factors associated with cyclist-open vehicle door collisions in Victoria, Australia were investigated using three complementary data sources: (1) police reported crashes (2000–2011); (2) hospital presentations (2000–2010), and (3) a sample of video footage from a naturalistic study of commuter cyclists in Melbourne (2009–2010). A total of 1247 police reported cyclist crashes and 401 hospital emergency department presentations were analysed. As a proportion of all cyclist crashes, cyclist-open vehicle door crashes accounted for 3.1% (hospital) and 8.4% (police). The majority of cyclists injured were: male (police: 67.1%; hospital: 65.8%); adults aged 18 years or older (police: 97.5 …