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This paper proposes a generalized multi-sensor fusion approach and a health risk assessment and decision-making (Health-RAD) algorithm for continuous and remote patient monitoring purposes using a Wireless Body Sensor Network (WBSN). Health-RAD determines the patient’s health condition severity level routinely and each time a critical issue is detected based on vital signs scores. Hence, a continuous health assessment and a monitoring of the improvement or the deterioration of the state of the patient is ensured. The severity level is represented by a risk variable whose values range between 0 and 1. The higher the risk value, the more critical the patient’s health condition is and the more it requires medical attention. Moreover, we calculate the score of a vital sign using its past and current value, thus assessing its status based on its evolution during a period of time and not only on sudden deviations. We …