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Nipah virus (NiV) and Hendra virus (HeV) are highly pathogenic zoonotic henipaviruses (HNVs) responsible for recurrent outbreaks of encephalitis and respiratory illness. As the current COVID-19 pandemic is gradually waning, attention is now being refocused on the nature of the next viral pandemic might be and what preparedness measures could be taken. Among almost all these discussions, the NiV Bangladesh strain (NiV-B) has been at the forefront of such concern by the scientific community, including the WHO and the Coalition for Epidemic Preparedness Innovations (CEPI). As another bat-borne virus, NiV infections are associated with human case fatality rates ranging from 40-95% and NiV-B is associated with significant human-to-human transmission. Currently, HNV G protein is both a vaccine antigen of interest for humans and a major viral target of monoclonal antibody therapy. Still, since the …