作者
Lin Wang, Nuha Alammar, Rajdeep Singh, Julie Nanavati, Yiran Song, Rahul Chaudhary, Gerard E Mullin
发表日期
2020/4/1
来源
Journal of the Academy of Nutrition and Dietetics
卷号
120
期号
4
页码范围
565-586
出版商
Elsevier
简介
Background
Irritable bowel syndrome (IBS) is the most common functional digestive condition in the industrialized world. The gut microbiota plays a key role in disease pathogenesis.
Objective
A systematic review and meta-analysis on case–control studies was conducted to determine whether there is gut microbial dysbiosis in participants with IBS in comparison with healthy controls and, if so, whether the dysbiosis pattern differs among IBS subtypes and geographic regions.
Methods
This review was conducted and reported according to the MOOSE (Meta-Analysis of Observational Studies in Epidemiology) 2000 and PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2009 guidelines. Research articles published up to May 9, 2018 were identified through MEDLINE (PubMed), Cochrane Central Register of Controlled Trials (Cochrane Library), ClinicalTrials.gov, EMBASE, and Web of …
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L Wang, N Alammar, R Singh, J Nanavati, Y Song… - Journal of the Academy of Nutrition and Dietetics, 2020