作者
Neeraj Shah, Rahul Chaudhary, Kathan Mehta, Vratika Agarwal, Jalaj Garg, Ronald Freudenberger, Larry Jacobs, David Cox, Karl B Kern, Nainesh Patel
发表日期
2016/9/12
期刊
JACC: Cardiovascular Interventions
卷号
9
期号
17
页码范围
1801-1811
出版商
American College of Cardiology Foundation
简介
Objectives
This study sought to determine whether “real-world” data supported the hypothesis that therapeutic hypothermia (TH) led to increased rates of stent thrombosis.
Background
TH, which is often instituted after cardiac arrest (CA) to improve neurologic outcomes, alters pharmacokinetics of antiplatelet medications, leading to a theoretical risk of stent thrombosis after percutaneous coronary intervention (PCI).
Methods
CA patients with acute myocardial infarction undergoing PCI were identified from the Nationwide Inpatient Sample from 2006 to 2011, with a defined primary outcome of stent thrombosis. The incidence of stent thrombosis in patients undergoing TH versus those not undergoing TH was compared using both logistic regression and propensity score matching.
Results
In this dataset, 49,109 CA patients underwent PCI for acute myocardial infarction from 2006 to 2011, of whom 1,193 (2.4%) underwent …
学术搜索中的文章
N Shah, R Chaudhary, K Mehta, V Agarwal, J Garg… - JACC: Cardiovascular Interventions, 2016