作者
Rahul Chaudhary, Jalaj Garg, Damon E Houghton, M Hassan Murad, Ashok Kondur, Rohit Chaudhary, Waldemar E Wysokinski, Robert D McBane II
发表日期
2021/4/1
来源
Mayo Clinic Proceedings: Innovations, Quality & Outcomes
卷号
5
期号
2
页码范围
388-402
出版商
Elsevier
简介
Objective
To evaluate differences in thromboinflammatory biomarkers between patients with severe coronavirus disease 2019 (COVID-19) infection/death and mild infection.
Patients and Methods
MEDLINE, Cochrane Central Register of Controlled Trials, EMBASE, EBSCO, Web of Science, and CINAHL databases were searched for studies comparing thromboinflammatory biomarkers in COVID-19 among patients with severe COVID-19 disease or death (severe/nonsurvivors) and those with nonsevere disease or survivors (nonsevere/survivors) from January 1, 2020, through July 11, 2020. Inclusion criteria were (1) hospitalized patients 18 years or older comparing severe/nonsurvivors vs nonsevere/survivors and (2) biomarkers of inflammation and/or thrombosis. A random-effects model was used to estimate the weighted mean difference (WMD) between the 2 groups of COVID-19 severity.
Results
We included 75 …
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R Chaudhary, J Garg, DE Houghton, MH Murad… - Mayo Clinic Proceedings: Innovations, Quality & …, 2021