作者
Kamel Mokhnache, Ahlem Karbab, Soraya Madoui, Hanane Khither, EL-Khamsa Soltani, Noureddine Charef, Lekhmici Arrar
发表日期
2019/10/15
期刊
Journal of Drug Delivery and Therapeutics
卷号
9
期号
5-s
页码范围
1-3
简介
The anti-inflammatory effects of the investigated compounds; Isoniazid, hydrazone, and Indomethacin were evaluated in this study. The experiment was performed using xylene induced topical ear edema method in mice model, at the dose of (0.5 mg/ear). Results showed that the compounds; Isoniazid, hydrazone, and Indomethacin exerted 85, 90 and 89% of inhibition percentages, respectively. The effect of hydrazone was statistically similar to the effect of indomethacin which is a standard anti-inflammatory drug.
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K Mokhnache, A Karbab, S Madoui, H Khither… - Journal of Drug Delivery and Therapeutics, 2019