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This study suggests an evolutionary technique namely symbiotic organisms search (SOS) algorithm based optimal designs of two different analogue very‐large‐scale integration circuits. The configurations considered here are nulling resistor compensation based complementary metal–oxide–semiconductor (CMOS) two‐stage op‐amp and two‐stage CMOS op‐amp with robust bias circuit. The prime goal of this work is the sizing of metal–oxide–semiconductor (MOS) transistors employing the SOS algorithm to optimise the area occupied by the individual circuit. Design results based on the SOS algorithm are authenticated with SPICE simulation. SPICE simulation results reveal that all the design specifications are firmly satisfied for both the circuits. Moreover, SPICE based results show that the SOS algorithm provides much better results compared to the earlier reported techniques regarding the gain, MOS area and …