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A non-fragile robust model predictive control (RMPC) is designed in the uncertain systems under bounded control signals. To this aim, a class of the nonlinear systems with additive uncertainty is considered in its general form. The RMPC synthesis could lead to the proper selection of the controller’s gains. Thus, the non-fragile RMPC design is translated into a minimization problem subjected to some constraints in terms of linear matrix inequality (LMI). Hence, the controller’s gains are computed by solving such a minimization problem. In some numerical examples, the suggested non-fragile RMPC is compared with the other methods. The simulation results demonstrate the effectiveness of the proposed RMPC in comparison with similar techniques.