作者
BA Moffat, DA Atchison, JM Pope
发表日期
2002/6/1
期刊
Vision research
卷号
42
期号
13
页码范围
1683-1693
出版商
Pergamon
简介
We report a new technique for non-invasively mapping the refractive index distribution through the eye lens using magnetic resonance micro-imaging. The technique is applied to map the refractive index distribution throughout the sagittal plane of 18 human eye lenses ranging in age from 14 to 82 years in vitro. The results are compared with standard models for the human eye lens. They confirm that the refractive index distribution, when plotted as a function of normalised lens radius, is a function of lens age and differs both between the equatorial and axial directions and between the anterior and posterior halves of the optical axis. The refractive index of the lens nucleus exhibits a significant reduction with age amounting to 3.4±0.6×10−4 years−1. The contribution of the gradient index (GRIN) to the lens power decreases by 0.286±0.067 D/year, accounting almost entirely for the estimated overall change in lens …
引用总数
2002200320042005200620072008200920102011201220132014201520162017201820192020202120222023202413689715467813610877875642