作者
Daniel So, Kevin Whelan, Megan Rossi, Mark Morrison, Gerald Holtmann, Jaimon T Kelly, Erin R Shanahan, Heidi M Staudacher, Katrina L Campbell
发表日期
2018/6/1
来源
The American journal of clinical nutrition
卷号
107
期号
6
页码范围
965-983
出版商
Elsevier
简介
Background
Dysfunction of the gut microbiota is frequently reported as a manifestation of chronic diseases, and therefore presents as a modifiable risk factor in their development. Diet is a major regulator of the gut microbiota, and certain types of dietary fiber may modify bacterial numbers and metabolism, including short-chain fatty acid (SCFA) generation.
Objective
A systematic review and meta-analysis were undertaken to assess the effect of dietary fiber interventions on gut microbiota composition in healthy adults.
Design
A systematic search was conducted across MEDLINE, EMBASE, CENTRAL, and CINAHL for randomized controlled trials using culture and/or molecular microbiological techniques evaluating the effect of fiber intervention on gut microbiota composition in healthy adults. Meta-analyses via a random-effects model were performed on alpha diversity, prespecified bacterial abundances including …
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