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This paper addresses the design and implementation of a real-time temperature monitoring system with applications in telemedicine. The system consists of a number of precision wireless thermometers which are conceived and realized to measure the patients' body temperature in hospitals and the intensive care units (ICUs). Each wireless thermometer incorporates an accurate semiconductor temperature sensor, a transceiver operating at 2.4 GHz and a microcontroller that controls the thermometer functionalities. An array of two thermometers are implemented and successfully evaluated in different scenarios, including free-space and in vivo tests. Also, an in-house developed computer software is used in order to visualize the measurements in addition to detecting rapid increase and alerting high body temperature. The agreement between the experimental data and reference temperature values is significant.