查看文章

Infectious keratitis is the fifth most prevalent cause of blindness worldwide. The primary diagnostic test to identify the pathogenic organism is the culture of corneal scraping. However microbial culture positivity is low and varies widely due to many underlying factors. Therefore, there is a need to understand the prevalence of such cases and what modern tools can be employed to diagnose them.

Contact lens usage, ocular injuries, and ocular surface disease have been reported to be primary risk factors for keratitis with infection of pathogens such as Staphylococcus spp., Pseudomonas aeruginosa, Fusarium spp., Candida spp., and Acanthamoeba spp. Advanced imaging techniques, such as in vivo confocal microscopy and anterior segment optical coherence tomography (OCT), and polymerase chain reaction (PCR) and other molecular techniques have been used to identify the …