作者
Henricus JM Handgraaf, Leonora SF Boogerd, Diederik J Höppener, A Peloso, BG Sibinga Mulder, Charlotte ES Hoogstins, Henk H Hartgrink, Cornelis JH van de Velde, J Sven D Mieog, Rutger-Jan Swijnenburg, Hein Putter, Marcello Maestri, Andries E Braat, John V Frangioni, Alexander L Vahrmeijer
发表日期
2017/8/1
期刊
European Journal of Surgical Oncology (EJSO)
卷号
43
期号
8
页码范围
1463-1471
出版商
WB Saunders
简介
Background
Several studies demonstrated that intraoperative near-infrared fluorescence (NIRF) imaging using indocyanine green (ICG) identifies (sub)capsular colorectal liver metastases (CRLM) missed by other techniques. It is unclear if this results in any survival benefit. This study evaluates long-term follow-up after NIRF-guided resection of CRLM using ICG.
Methods
First, patients undergoing resection of CRLM with or without NIRF imaging were analyzed retrospectively. Perioperative details, liver-specific recurrence-free interval and overall survival were compared. Second, the prognosis of patients in whom additional metastases were identified solely by NIRF was studied.
Results
Eighty-six patients underwent resection with NIRF imaging and 87 without. In significantly more patients of the NIRF imaging cohort additional metastases were identified during surgery (25% vs. 13%, p = 0.04). Tumors identified solely …
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HJM Handgraaf, LSF Boogerd, DJ Höppener, A Peloso… - European Journal of Surgical Oncology (EJSO), 2017