作者
Rafael Suau, Rodrigo Rico, Juan Manuel López-Romero, Francisco Nájera, Antonio Ruiz, Francisco Javier Ortiz-López
发表日期
2002/1/1
期刊
Arkivoc
卷号
2002
期号
5
页码范围
62-72
出版商
ARKAT USA, Inc.
简介
Double cyclization of aryloxy-phenyl acetamides is promoted by oxalyl chloride/stannyl chloride and gives 3, 4-dioxocularine and aristocularine alkaloids. Rearrangement of the dibenzoxepine ring prior to the second cyclization produces xanthene derivatives. The synthesized cularinoids exhibit significant activity against various tumoral cell lines.
引用总数
学术搜索中的文章
R Suau, R Rico, JM López-Romero, F Nájera, A Ruiz… - Arkivoc, 2002