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This study explored how changes in neighborhood structural characteristics predicted variation in gang versus non-gang homicides in a policing division of the Los Angeles Police Department (LAPD). Longitudinal negative binomial models were examined to test the relationship between-neighborhood structural covariates with gang and non-gang homicides over a 35-year period. This study highlights the potential to estimate temporal effects not captured by cross-sectional analyses alone. The results underscore a unique feature that distinguishes gang homicides from other forms of non-gang violence, its tenacious clustering, and spatial dependence over time.