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<?Pub Dtl=""?> Multimodal medical image fusion, as a powerful tool for the clinical applications, has developed with the advent of various imaging modalities in medical imaging. The main motivation is to capture most relevant information from sources into a single output, which plays an important role in medical diagnosis. In this paper, a novel fusion framework is proposed for multimodal medical images based on non-subsampled contourlet transform (NSCT). The source medical images are first transformed by NSCT followed by combining low- and high-frequency components. Two different fusion rules based on phase congruency and directive contrast are proposed and used to fuse low- and high-frequency coefficients. Finally, the fused image is constructed by the inverse NSCT with all composite coefficients. Experimental results and comparative study show that the proposed fusion framework provides an …