作者
James KY Hooi, Wan Ying Lai, Wee Khoon Ng, Michael MY Suen, Fox E Underwood, Divine Tanyingoh, Peter Malfertheiner, David Y Graham, Vincent WS Wong, Justin CY Wu, Francis KL Chan, Joseph JY Sung, Gilaad G Kaplan, Siew C Ng
发表日期
2017/8/1
来源
Gastroenterology
卷号
153
期号
2
页码范围
420-429
出版商
WB Saunders
简介
Background & Aims
The epidemiology of Helicobacter pylori infection has changed with improvements in sanitation and methods of eradication. We performed a systematic review and meta-analysis to evaluate changes in the global prevalence of H pylori infection.
Methods
We performed a systematic search of the MEDLINE and EMBASE databases for studies of the prevalence of H pylori infection published from January 1, 1970 through January 1, 2016. We analyzed data based on United Nations geoscheme regions and individual countries. We used a random effects model to calculate pooled prevalence estimates with 95% confidence intervals (CIs), weighted by study size. We extrapolated 2015 prevalence estimates to obtain the estimated number of individuals with H pylori infection.
Results
Among 14,006 reports screened, we identified 263 full-text articles on the prevalence of H pylori infection; 184 were …
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