作者
Angelo Territo, Alberto Piana, Matteo Fontana, Pietro Diana, Andrea Gallioli, Josep Maria Gaya, Jordi Huguet, Pavel Gavrilov, Óscar Rodríguez-Faba, Carmen Facundo, Lluis Guirado, Joan Palou, Alex Mottrie, Alberto Breda
发表日期
2021/12/1
期刊
European Urology
卷号
80
期号
6
页码范围
738-745
出版商
Elsevier
简介
Background
Kidney transplantation (KT) is the best renal replacement treatment. The rewarming time is associated with ischemia/reperfusion damage. In both the open (open KT [OKT]) and the robotic (robotic-assisted KT [RAKT]) approaches, ice slush is used to maintain graft temperature (T°) below 20 °C. This may result in nonhomogeneous graft T° maintenance and, particularly during RAKT where the graft is completely inside the abdominal cavity, rises concerns regarding systemic hypothermia.
Objective
To design a cold ischemia device (CID) to maintain a constant and homogeneous low graft T° during surgery.
Design, setting, and participants
In IDEAL phase 0, a CID was developed and tested to determine its cooling effect on the kidney inside a closed system at 37.5 °C, by comparing it with kidney alone versus a gauze-jacket filled with ice slush. The CID was evaluated in pigs undergoing OKT and RAKT …
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A Territo, A Piana, M Fontana, P Diana, A Gallioli… - European Urology, 2021