作者
Caroline Huart, Carl M Philpott, Aytug Altundag, Alexander W Fjaeldstad, Johannes Frasnelli, Simon Gane, Julien W Hsieh, Eric H Holbrook, Iordanis Konstantinidis, Basile N Landis, Alberto Macchi, Christian A Mueller, Simona Negoias, Jayant M Pinto, Sophia C Poletti, Vijay R Ramakrishnan, Philippe Rombaux, Jan Vodicka, Antje Welge‐Lüessen, Katherine L Whitcroft, Thomas Hummel
发表日期
2021/7
期刊
International forum of allergy & rhinology
卷号
11
期号
7
页码范围
1041-1046
简介
The frequent association between coronavirus disease 2019 (COVID‐19) and olfactory dysfunction is creating an unprecedented demand for a treatment of the olfactory loss. Systemic corticosteroids have been considered as a therapeutic option. However, based on current literature, we call for caution using these treatments in early COVID‐19–related olfactory dysfunction because: (1) evidence supporting their usefulness is weak; (2) the rate of spontaneous recovery of COVID‐19–related olfactory dysfunction is high; and (3) corticosteroids have well‐known potential adverse effects. We encourage randomized placebo‐controlled trials investigating the efficacy of systemic steroids in this indication and strongly emphasize to initially consider smell training, which is supported by a robust evidence base and has no known side effects.
引用总数
2020202120222023202411127165
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