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A 0.45-V low-power 0.18 μm CMOS OOK/FSK RF receiver for implantable medical applications is proposed. The receiver utilizes a wake-up mechanism to adjust its power consumption automatically by reading the amplitude of the input wireless OOK/FSK modulated RF signal directly. No additional wireless wake-up commands are required. Such a normally-off and instanton scheme reduces the power consumption of this receiver significantly. The power consumption is 129 μW in sleep mode and 352 μW in wake-up mode. Other techniques, such as third-orderharmonic cancellation, subharmonic mixing, and forward body biasing are also adopted for better linearity, higher LO-to-RF isolation, and lower VDD, respectively. The measurement results show that the proposed receiver consumes only 2.6 nJ/bit (OOK) and 1 nJ/bit (FSK) to achieve the sensitivities of -55 dBm (OOK) and -53.5 dBm (FSK) in BER <; 10-3 …