作者
Pen-Li Huang, Po-Hung Kuo, Yu-Jie Huang, Hsin-Hung Liao, Yao-Joe Joseph Yang, Tao Wang, Yao-Hung Wang, Shey-Shi Lu
发表日期
2012
期刊
IEEE Transactions on Industrial Electronics
卷号
59
期号
3
页码范围
1578-1587
出版商
IEEE
简介
A system-on-a-chip (SOC) with integrated drug reservoirs for drug delivery is proposed. Electrolysis is used to generate microbubbles, which are employed as a force to open the reservoirs and release the drug. Wireless components, including an on/off keying receiver, microcontrol unit, regulator, clock divider, and power-on reset, are integrated for remote drug activation. The proposed microchip is fabricated by Taiwan Semiconductor Manufacturing Company 0.35-μm CMOS technology followed by post-IC processing. The total size is 2.48 mm 2 , and the power consumption is 7.57 mW. The in vitro experiment has proven the feasibility of the proposed drug delivery SOC.
学术搜索中的文章
PL Huang, PH Kuo, YJ Huang, HH Liao, YJJ Yang… - IEEE Transactions on Industrial Electronics, 2011