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The neglection of thermal-mechanical interaction of the high-speed motorized spindle system may lead to modeling errors of thermal and dynamic characteristics. In this work, the thermal-mechanical interaction mechanism is analyzed, and a closed-loop iterative modeling method for thermal and dynamical characteristics is proposed to improve the modeling accuracy. The nonlinear dynamic model with thermal effects of the spindle system under unbalanced magnetic pull and unbalanced mass excitation is established to evaluate its transient dynamic behavior. A multi-node thermal resistance network model of the motorized spindle system considering the nonlinear vibration of the spindle system is established to evaluate transient thermal behavior. Based on the load-displacement relationship, the nonlinear stiffness and restoring force model of bearing considering thermal effects and nonlinear vibration is …