作者
Sadako Motoyama, Masayoshi Sarai, Hiroto Harigaya, Hirofumi Anno, Kaori Inoue, Tomonori Hara, Hiroyuki Naruse, Junichi Ishii, Hitoshi Hishida, Nathan D Wong, Renu Virmani, Takeshi Kondo, Yukio Ozaki, Jagat Narula
发表日期
2009/6/30
期刊
Journal of the American College of Cardiology
卷号
54
期号
1
页码范围
49-57
出版商
American College of Cardiology Foundation
简介
Objectives
In a computed tomographic (CT) angiography study, we identified the characteristics of atherosclerotic lesions that were associated with subsequent development of acute coronary syndrome (ACS).
Background
The CT characteristics of culprit lesions in ACS include positive vessel remodeling (PR) and low-attenuation plaques (LAP). These 2 features have been observed in the lesions that have already resulted in ACS, but their prospective relation to ACS has not been previously described.
Methods
In 1,059 patients who underwent CT angiography, atherosclerotic lesions were analyzed for the presence of 2 features: PR and LAP. The remodeling index, and plaque and LAP areas and volumes were calculated. The plaque characteristics of lesions resulting in ACS during the follow-up of 27 ± 10 months were evaluated.
Results
Of the 45 patients showing plaques with both PR and LAP (2-feature positive …
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