作者
Marianne Leruez-Ville, Yves Ville
发表日期
2017/1/1
来源
Best practice & research Clinical obstetrics & gynaecology
卷号
38
页码范围
97-107
出版商
Baillière Tindall
简介
Highlights
- Recent data highlight the true burden of non-primary maternal infection in congenital CMV infection.
- Accurate diagnosis of maternal primary infection is achievable.
- Diagnosis of fetal infection by amniocentesis is reliable.
- Establishing the prognosis of an infected fetus is achievable with over 90% positive and negative predictive values.
- First successful non-randomized study using valaciclovir for symptomatic fetuses.
Cytomegalovirus (CMV) congenital infection affects 0.7% of live births worldwide and is the leading cause of congenital neurological handicap of infectious origin. However, systematic screening for this infection has not been implemented in pregnancy or at birth in any country. This apparent paradox had been justified by persisting gaps in the knowledge of this congenital infection: uncertain epidemiological data, difficulty in the diagnosis of maternal infection, absence of validated prenatal …
学术搜索中的文章
M Leruez-Ville, Y Ville - Best practice & research Clinical obstetrics & …, 2017