作者
Guillaume Fahrni, Nicolas A Karakatsanis, Giulia Di Domenicantonio, Valentina Garibotto, Habib Zaidi
发表日期
2019/9/1
期刊
European radiology
卷号
29
页码范围
4812-4821
出版商
Springer Berlin Heidelberg
简介
Purpose
Single-pass whole-body (WB) 18F-FDG PET/CT imaging is routinely employed for the clinical assessment of malignant, infectious, and inflammatory diseases. Our aim in this study is the systematic clinical assessment of lesion detectability in multi-pass WB parametric imaging enabling direct imaging of the highly quantitative 18F-FDG influx rate constant Ki, as a complement to standard-of-care standardized uptake value (SUV) imaging for a range of oncologic studies.
Methods
We compared SUV and Ki images of 18 clinical studies of different oncologic indications (lesion characterization and staging) including standard-of-care SUV and dynamic WB PET protocols in a single session. The comparison involved both the visual assessment and the quantitative evaluation of SUVmean, SUVmax, Kimean, Kimax, tumor-to-background ratio (TBRSUV …
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G Fahrni, NA Karakatsanis, G Di Domenicantonio… - European radiology, 2019