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Mammographic mass segmentation plays an important role in computer-aided diagnosis systems. It is very challenging because masses are always of low contrast with ambiguous margins, connected with the normal tissues, and of various scales and complex shapes. To effectively detect true boundaries of mass regions, we propose a feature embedded vector-valued contour-based level set method with relaxed shape constraint. In particular, we initially use the contour-based level set method to obtain the initial boundaries on the smoothed mammogram as the shape constraint. To prevent the contour leaking and meanwhile preserve the radiative characteristics of specific malignant masses, afterward, we relax the obtained shape constraint by analyzing possible valid regions around the initial boundaries. The relaxed shape constraint is then used to design a novel stopping function for subsequent vector-valued …