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A 3-year old pug bitch was presented to the Referral Veterinary Polyclinic, IVRI, Bareilly, with history of anestrus since last one year despite having normal body condition and appetite. Vaginal examination revealed normal genitalia without any abnormalities. For induction of estrus, bitch was treated with cabergoline orally till the bitch shows proestral bleeding. After 10 days of treatment, bitch showed proestrous bleeding and on 12th days of proestrus, the vaginal cytology revealed presence of more than 90% of cornified cells and advised for breeding the bitch on alternative days until bitch rejects the male. After 45 days of mating the bitch was again presented to clinics for pregnancy diagnosis. Ultrasonographic examination revealed, 45 day old pregnancy. Cabergoline can be used as master drug to induce fertile estrus in any breed of dogs without much side effect.