作者
Maharajan Lavanya, Sellappan Selvaraju, Balaganur Krishnappa, Narayanan Krishnaswamy, Govindasamy Nagarajan, Harendra Kumar
发表日期
2022/1
来源
Andrology
卷号
10
期号
1
页码范围
92-104
简介
Background
Terminally differentiated mammalian sperm are exposed to gradients of viscosity, pH, and osmolality both in the male and female reproductive tract during their perilous journey to quest the ovum. The complex physicochemical factors play an integral role in preparing sperm for the fertilization process.
Objectives
To elucidate the influence of the reproductive tract microenvironment especially viscosity, pH, and osmolality in regulating sperm functional and fertilization competence.
Materials and Methods
The data used in this review were collected from the research papers and online databases focusing on the influence of viscosity, pH, and osmolality on sperm function.
Discussion
The gradients of viscosity, pH, and osmolality exist across various segments of the male and female reproductive tract. The changes in the viscosity create a physical barrier, pH aid in capacitation and hyperactivation, and …
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