作者
Marta Ondrésik, Fatima R Azevedo Maia, Alain da Silva Morais, Ana C Gertrudes, Ana H Dias Bacelar, Cristina Correia, Cristiana Gonçalves, Hajer Radhouani, Rui Amandi Sousa, Joaquim M Oliveira, Rui L Reis
发表日期
2017/4
来源
Biotechnology and Bioengineering
卷号
114
期号
4
页码范围
717-739
简介
Osteoarthritis (OA) affects a large number of the population, and its incidence is showing a growing trend with the increasing life span. OA is the most prevalent joint condition worldwide, and currently, there is no functional cure for it. This review seeks to briefly overview the management of knee OA concerning standardized pharmaceutical and clinical approaches, as well as the new biotechnological horizons of OA treatment. The potential of biomaterials and state of the art of advanced therapeutic approaches, such as cell and gene therapy focused primarily on cartilage regeneration are the main subjects of this review. Biotechnol. Bioeng. 2017;114: 717–739. © 2016 Wiley Periodicals, Inc.
学术搜索中的文章
M Ondrésik, FR Azevedo Maia, A da Silva Morais… - Biotechnology and Bioengineering, 2017