作者
Tianmiao Hua, Xiangrui Li, Lihua He, Yifeng Zhou, Yongchang Wang, Audie G Leventhal
发表日期
2006/1/1
期刊
Neurobiology of aging
卷号
27
期号
1
页码范围
155-162
出版商
Elsevier
简介
Visual function declines with age. Using extracellular single-unit in vivo recordings, we compared the function of primary visual cortical (area 17) cells in young and old paralyzed, anesthetized cats. The results reveal that cortical neurons in old cats exhibit higher visually evoked responses, higher spontaneous activities, lower signal-to-noise ratios, and weaker orientation and direction selectivity than do cells in young adult cats. These findings are consistent with previously reported age related declines in cortical function in senescent macaque monkeys. Thus, similar declines in cortical function accompany old age in different mammalian species with well developed cortices.
引用总数
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学术搜索中的文章
T Hua, X Li, L He, Y Zhou, Y Wang, AG Leventhal - Neurobiology of aging, 2006