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The deposition of potentially toxic mercury (Hg) in various ecosystems and subsequent entry into the food chain pose serious concerns to the ecosystem, biodiversity, and public health. In terms of toxicity, Hg is considered as a neurotoxin and capable to augment in food chains and bind to the thiol functional entity in living tissue. Moreover, methylated mercury (CH₃Hg⁺) is a highly toxic form of mercury and extremely difficult to remove from living bodies. Mercury methylation is mainly conducted by microbial and/or chemical processes under appropriate conditions. The mechanisms associated with mercury methylation inside the environment, their sources, production/degradation rate, and transport into the living organisms are not well understood. In addition, efficient and sustainable remediation strategies are essential to employ for mercury removal. Therefore, this review signifies a possible mechanism for mercury …