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Hand gesture recognition has attracted the attention of many researchers due to its wide applications in robotics, games, virtual reality, sign language and human-computer interaction. Sign language is a structured form of hand gestures and the most effective communication way among hear-impaired people. Developing an efficient sign language recognition system to recognize dynamic isolated gestures encounters three major challenges, namely, hand segmentation, hand shape feature representation and gesture sequence recognition. Traditional sign language recognition methods utilize color-based hand segmentation algorithms to segment hands, hand-crafted feature extraction for hand shape representation and Hidden Markov Model (HMM) for sequence recognition. In this paper, a novel framework is proposed for signer-independent sign language recognition using multiple deep learning architectures …