作者
Alexandra D Frolkis, Jonathan Dykeman, María E Negrón, Jennifer Debruyn, Nathalie Jette, Kirsten M Fiest, Talia Frolkis, Herman W Barkema, Kevin P Rioux, Remo Panaccione, Subrata Ghosh, Samuel Wiebe, Gilaad G Kaplan
发表日期
2013/11/1
来源
Gastroenterology
卷号
145
期号
5
页码范围
996-1006
出版商
WB Saunders
简介
Background & Aims
The inflammatory bowel diseases (IBDs) are chronic diseases that often require surgery. However, the risk of requirement of surgery over time has not been well characterized. We performed a systematic review and meta-analysis to establish the cumulative risk of surgery among patients with IBD and evaluated how this risk has changed over time.
Methods
We searched Medline, EMBASE, PubMed, and conference proceedings (2009–2012) on May 8, 2013, for terms related to IBD and intestinal surgery. Two reviewers screened 8338 unique citations to identify 486 for full-text review. The analysis included population-based studies published as articles (n = 26) and abstracts (n = 4) that reported risks of surgery at 1, 5, or 10 years after a diagnosis of Crohn's disease and/or ulcerative colitis. The trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.
Results …
学术搜索中的文章
AD Frolkis, J Dykeman, ME Negrón, J Debruyn, N Jette… - Gastroenterology, 2013