作者
Luke YC Chen, Catherine M Biggs, Shahin Jamal, Sophie Stukas, Cheryl L Wellington, Mypinder S Sekhon
发表日期
2021/5/18
期刊
Cell Reports Medicine
卷号
2
期号
5
出版商
Elsevier
简介
Data suggest that interleukin (IL)-6 blockade could reduce mortality in severe COVID-19, yet IL-6 is only modestly elevated in most patients. Chen et al. describe the role of soluble interleukin-6 receptor (sIL-6R) in IL-6 trans-signaling and how understanding the IL-6:sIL-6R axis might help define and treat COVID-19 cytokine storm syndrome.
学术搜索中的文章
LYC Chen, CM Biggs, S Jamal, S Stukas… - Cell Reports Medicine, 2021