作者
Deanne K Thompson, Jian Chen, Richard Beare, Christopher L Adamson, Rachel Ellis, Zohra M Ahmadzai, Claire E Kelly, Katherine J Lee, Andrew Zalesky, Joseph YM Yang, Rodney W Hunt, Jeanie LY Cheong, Terrie E Inder, Lex W Doyle, Marc L Seal, Peter J Anderson
发表日期
2016/7/1
期刊
NeuroImage
卷号
134
页码范围
328-337
出版商
Academic Press
简介
Objective
To use structural connectivity to (1) compare brain networks between typically and atypically developing (very preterm) children, (2) explore associations between potential perinatal developmental disturbances and brain networks, and (3) describe associations between brain networks and functional impairments in very preterm children.
Methods
26 full-term and 107 very preterm 7-year-old children (born < 30 weeks' gestational age and/or < 1250 g) underwent T1- and diffusion-weighted imaging. Global white matter fibre networks were produced using 80 cortical and subcortical nodes, and edges were created using constrained spherical deconvolution-based tractography. Global graph theory metrics were analysed, and regional networks were identified using network-based statistics. Cognitive and motor function were assessed at 7 years of age.
Results
Compared with full-term children, very preterm …
学术搜索中的文章
DK Thompson, J Chen, R Beare, CL Adamson, R Ellis… - Neuroimage, 2016