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Infections caused by drug-resistant strains pose a serious threat to human health. Most bacterial infections are related to biofilms. The generation of a bacterial biofilm greatly reduces the antibacterial efficiency of antibiotics and some traditional antibacterial drugs, and it is very important to develop antibacterial drugs to replace antibiotics. Here, encouraged by the promising magnetic control technology of micro/nanorobots, the synergistic antibacterial strategy of a dandelion-like magnetically-controlled multifunctional hierarchical magnetic biomimetic nanozyme, Fe3O4@SiO2@dendritic mesoporous silica@small-Fe3O4 nanoparticles (FSDMSsF NPs), was developed to be effective against bacterial biofilms. FSDMSsF NPs showed great magnetic properties and peroxidase-like activities, and could act as catalytic carriers for the production of hydroxyl radicals that are highly toxic to bacteria in a low-concentration …