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Six years have passed since Smart Specialisation was incorporated in European Cohesion Policy and became the reference framework for innovation policy in European regions and countries. One year before the beginning of the new Cohesion Policy cycle, it is now the right time to strike a balance in the Smart Specialisation experience and support the design of the upcoming generation of policy strategies with sound evidence on what has worked and what not.

At the time of writing, the dreadful COVID-19 pandemic is sweeping the planet, causing severe health, social and economic hardship. Such difficult circumstances triggered the deployment of a wide array of policy initiatives at European Union (EU), national and regional levels to mitigate the COVID-19 economic and social crisis, along with the necessary health measures. Governments have made available a considerable set of initiatives and amount of …