作者
Fiona J Kinnear, Elaine Wainwright, Rachel Perry, Fiona E Lithander, Graham Bayly, Alyson Huntley, Jennifer Cox, Julian PH Shield, Aidan Searle
发表日期
2019/7/1
来源
BMJ open
卷号
9
期号
7
页码范围
e030290
出版商
British Medical Journal Publishing Group
简介
Objectives
Individuals with heterozygous familial hypercholesterolaemia (FH) are at high risk of developing cardiovascular disease (CVD). This risk can be substantially reduced with lifelong pharmacological and lifestyle treatment; however, research suggests adherence is poor. We synthesised the qualitative research to identify enablers and barriers to treatment adherence.
Design
This study conducted a thematic synthesis of qualitative studies.
Data sources
MEDLINE, Embase, PsycINFO via OVID, Cochrane library and CINAHL databases and grey literature sources were searched through September 2018.
Eligibility criteria
We included studies conducted in individuals with FH, and their family members, which reported primary qualitative data regarding their experiences of and beliefs about their condition and its treatment.
Data extraction and synthesis
Quality assessment was undertaken using the Critical Appraisal …
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FJ Kinnear, E Wainwright, R Perry, FE Lithander… - BMJ open, 2019