作者
Pietro Bertoglio, Giulia Querzoli, Luigi Ventura, Vittorio Aprile, Maria A Cattoni, Dania Nachira, Filippo Lococo, Maria Rodriguez Perez, Francesco Guerrera, Fabrizio Minervini, Letizia Gnetti, Diana Bacchin, Francesca Franzi, Guido Rindi, Salvatore Bellafiore, Federico Femia, Andrea Viti, Giuseppe S Bogina, Peter Kestenholz, Enrico Ruffini, Massimiliano Paci, Stefano Margaritora, Andrea S Imperatori, Marco Lucchi, Luca Ampollini, Alberto C Terzi
发表日期
2021/2
期刊
Journal of surgical oncology
卷号
123
期号
2
页码范围
560-569
简介
Background and Objectives
Adenocarcinoma patterns could be grouped based on clinical behaviors: low‐ (lepidic), intermediate‐ (papillary or acinar), and high‐grade (micropapillary and solid). We analyzed the impact of the second predominant pattern (SPP) on disease‐free survival (DFS).
Methods
We retrospectively collected data of surgically resected stage I and II adenocarcinoma. Selection criteria: anatomical resection with lymphadenectomy and pathological N0. Pure adenocarcinomas and mucinous subtypes were excluded. Recurrence rate and factors affecting DFS were analyzed according to the SPP focusing on intermediate‐grade predominant pattern adenocarcinomas.
Results
Among 270 patients, 55% were male. The mean age was 68.3 years. SPP pattern appeared as follows: lepidic 43.0%, papillary 23.0%, solid 14.4%, acinar 11.9%, and micropapillary 7.8%. The recurrence rate was 21.5 …
学术搜索中的文章
P Bertoglio, G Querzoli, L Ventura, V Aprile, MA Cattoni… - Journal of Surgical Oncology, 2021