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Object detection in remote-sensing images is a crucial task in the fields of Earth observation and computer vision. Despite impressive progress in modern remote-sensing object detectors, there are still three challenges to overcome: 1) complex background interference; 2) dense and cluttered arrangement of instances; and 3) large-scale variations. These challenges lead to two key deficiencies, namely, coarse features and coarse samples, which limit the performance of existing object detectors. To address these issues, in this article, a novel coarse-to-fine framework (CoF-Net) is proposed for object detection in remote-sensing imagery. CoF-Net mainly consists of two parallel branches, namely, coarse-to-fine feature adaptation (CoF-FA) and coarse-to-fine sample assignment (CoF-SA), which aim to progressively enhance feature representation and select stronger training samples, respectively. Specifically, CoF-FA …