作者
Serhan Küpeli, Tuncay Hazırolan, Ali Varan, Deniz Akata, Dursun Alehan, Mutlu Hayran, Aytekin Besim, Münevver Büyükpamukçu
发表日期
2010/2/20
期刊
Journal of clinical oncology
卷号
28
期号
6
页码范围
1025-1030
出版商
American Society of Clinical Oncology
简介
Purpose
To detect pathologies in coronary arteries by computed tomography angiography (CTA) in survivors of childhood Hodgkin's lymphoma who have been treated with radiotherapy and/or cardiotoxic agents.
Patients and Methods
Patients with HL who have been in remission for at least 2 years after completion of therapy were included. CBC, lipid profile, urine analysis, brain natriuretic peptide, troponin-T, creatinine kinase–myocardial band, ECG, telecardiography, echocardiography, and CTA of the patients were performed. Cardiac vascular abnormalities were noted.
Results
A total of 119 patients were included in the study. In 19 patients (16%), we found coronary artery abnormalities. There was a significant difference between the patients who received mediastinal radiotherapy and those who did not (P = .02). By multivariate analysis, in patients receiving mediastinal radiotherapy the risk of developing a …
学术搜索中的文章
S Küpeli, T Hazırolan, A Varan, D Akata, D Alehan… - Journal of clinical oncology, 2010