作者
Adriana Ammassari, Rita Murri, Patrizio Pezzotti, Maria Paola Trotta, Laura Ravasio, Patrizio De Longis, Sergio Lo Caputo, Pasquale Narciso, Sergio Pauluzzi, Giampiero Carosi, Salvatore Nappa, Paola Piano, Crescenzo M Izzo, Miriam Lichtner, Giovanni Rezza, Antonella d'Arminio Monforte, Giuseppe Ippolito, Mauro Moroni, Albert W Wu, Andrea Antinori, AdICONA Study Group
发表日期
2001/12/15
期刊
JAIDS Journal of Acquired Immune Deficiency Syndromes
卷号
28
期号
5
页码范围
445-449
出版商
LWW
简介
Objectives: To identify variables predictive of nonadherence to highly active antiretroviral therapy (HAART) and to assess whether self-reported symptoms or medication side effects are related to adherence.
Design: Cross-sectional multicenter study Adherence Italian Cohort Naive Antiretrovirals [AdICONA] within the Italian Cohort Naive Antiretrovirals (ICONA).
Methods: Participants receiving HAART completed a 16-item self-administered questionnaire to assess nonadherence in the last 3 days as well as the type and intensity of 24 common HIV-and HAART-related symptoms experienced during the last 4 weeks.
Results: From May 1999 to March 2000, 358 persons were enrolled: 22% reported nonadherence and were less likely to have HIV RNA< 500 copies/ml (odds ratio= 0.51; 95% confidence interval: 0.31-0.85). Frequency of moderate/severe symptoms or medication side effects in nonadherent participants …
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A Ammassari, R Murri, P Pezzotti, MP Trotta, L Ravasio… - JAIDS Journal of Acquired Immune Deficiency …, 2001