作者
Robert A Power, Stacy Steinberg, Gyda Bjornsdottir, Cornelius A Rietveld, Abdel Abdellaoui, Michel M Nivard, Magnus Johannesson, Tessel E Galesloot, Jouke J Hottenga, Gonneke Willemsen, David Cesarini, Daniel J Benjamin, Patrik KE Magnusson, Fredrik Ullén, Henning Tiemeier, Albert Hofman, Frank JA Van Rooij, G Bragi Walters, Engilbert Sigurdsson, Thorgeir E Thorgeirsson, Andres Ingason, Agnar Helgason, Augustine Kong, Lambertus A Kiemeney, Philipp Koellinger, Dorret I Boomsma, Daniel Gudbjartsson, Hreinn Stefansson, Kari Stefansson
发表日期
2015/7/1
期刊
Nature Neuroscience
卷号
18
期号
7
页码范围
953-955
出版商
Nature Research
简介
We tested whether polygenic risk scores for schizophrenia and bipolar disorder would predict creativity. Higher scores were associated with artistic society membership or creative profession in both Icelandic (P= 5.2× 10− 6 and 3.8× 10− 6 for schizophrenia and bipolar disorder scores, respectively) and replication cohorts (P= 0.0021 and 0.00086). This could not be accounted for by increased relatedness between creative individuals and those with psychoses, indicating that creativity and psychosis share genetic roots.
引用总数
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