作者
Mercy Nyamewaa Asiedu, Anish Simhal, Usamah Chaudhary, Jenna L Mueller, Christopher T Lam, John W Schmitt, Gino Venegas, Guillermo Sapiro, Nimmi Ramanujam
发表日期
2018/12/18
期刊
IEEE Transactions on Biomedical Engineering
卷号
66
期号
8
页码范围
2306-2318
出版商
IEEE
简介
Goal
In this paper, we propose methods for (1) automatic feature extraction and classification for acetic acid and Lugol's iodine cervigrams and (2) methods for combining features/diagnosis of different contrasts in cervigrams for improved performance.
Methods
We developed algorithms to pre-process pathology-labeled cervigrams and extract simple but powerful color and textural-based features. The features were used to train a support vector machine model to classify cervigrams based on corresponding pathology for visual inspection with acetic acid, visual inspection with Lugol's iodine, and a combination of the two contrasts.
Results
The proposed framework achieved a sensitivity, specificity, and accuracy of 81.3%, 78.6%, and 80.0%, respectively, when used to distinguish cervical intraepithelial neoplasia (CIN+) relative to normal and benign tissues. This is superior to the average values achieved by three …
引用总数
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