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Weight changes occur throughout the cancer trajectory. Most research has focused on changes during or after treatment, so clinical significance of change at diagnosis remains unclear. This study aimed to determine prevalence, predictors and prognostic significance of weight changes at diagnosis in outpatients with solid tumours presenting to a tertiary academic medical centre.

A retrospective study of the electronic medical record was conducted (n = 6477). Those with weight recorded within 6 months of cancer diagnosis (pre-diagnosis, T₀) and 2 subsequent weights (diagnosis, T₁; final visit, T₂) were identified (n = 4258). Percentage weight change was categorised into four bands (0.1–2.4%; 2.5–5%; 5.01–9.9%; ≥ 10%) for gain and loss. A stable category was also included.

Mean age is …